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Aromatic amino acids (AAA)〔 are amino acids that include an aromatic ring. Examples include: * Among 20 standard amino acids: * * phenylalanine * * tryptophan * * histidine * * tyrosine * Others: * * thyroxine * * 5-hydroxytryptophan * * L-DOPA Phenylalanine → tyrosine → L-DOPA → (dopamine) → (epinephrine) → (norepinephrine) Tryptophan → 5-hydroxytryptophan → (serotonin) Histidine → (histamine) Phenylalanine → tyrosine → thyroxine Phenylalanine, histidine, and tryptophan are essential amino acids for animals. Since they are not synthesized in the human body, they must be derived from the diet. Tyrosine is semi-essential; it can be synthesized, but only from phenylalanine. A lack of the enzyme phenylalanine hydroxylase, used in tyrosine synthesis, causes phenylketonuria, and concurrently renders tyrosine an essential amino acid. Animals get aromatic amino acids from diet, but all plants and micro-organisms must synthesize their aromatic amino acids through the metabolically costly shikimate pathway in order to make proteins. Herbicides and antibiotics work by inhibiting enzymes involved in aromatic acid synthesis, thereby rendering them toxic to plants and micro-organisms but not to animals. All plants and micro-organisms must synthesize their aromatic amino acids through the shikimate pathway in order to make proteins, unlike animals, which obtain them through their diet. Because of the energy intensive nature of amino acid biosynthesis, animals have lost these costly metabolic pathways, since they can obtain aromatic amino acids by ingesting other organisms. Herbicides and antibiotics take advantage of this by inhibiting enzymes involved in aromatic acid synthesis, thereby rendering them toxic to plants and micro-organisms but not animals. ==See also== * Aromatic L-amino acid decarboxylase 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Aromatic amino acids」の詳細全文を読む スポンサード リンク
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